Case Study 6: Lenalidomide Hydrate vs Solvate

Scope

  • Develop protocols to understand the thermal stability of individual polymorphs
  • Provide mechanistic understanding on desolvation/ dehydration structural arrangement or cooperative mechanism of individual polymorphs

In Situ Variable Temperature- FTIR ATR Measurements

Chennuru R, Muthudoss P, Voguri RS, Ramakrishnan S, Vishweshwar P, Babu RR, Mahapatra S. Iso-structurality induced solid phase transformations: a case study with lenalidomide. Crystal Growth & Design. 2017 Feb 1;17(2):612-28.

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